Sequential diagnosis and treatment for colon cancer via derived iridium and indocyanine green hybrid nanomicelles.Liang Yu, Yan Peng, Linping Jiang, Liyan Qiu*. ACS Applied Materials & Interfaces, 2023. (pdf)
Oligochitosan-based nanovesicles for nonalcoholic fatty liver disease treatment via the FXR/miR-34a/SIRT1 regulatory loop. Mengjie Kong, Yan Peng, Liyan Qiu*.Acta Biomaterialia. 2023. (pdf)
2022年
Drug-induced self-assembled nanovesicles for doxorubicin resistance reversal via autophagy inhibition and delivery synchronism, Juan Wang, Liyan Qiu*, Theranostics, 2022. (pdf)
Responsive oligochitosan nano-vesicles with ursodeoxycholic acid and exenatide for NAFLD synergistic therapy via SIRT1, Pengchao Xie, Yan Peng, Liyan Qiu*, Carbohydrate Polymers, 2022. (pdf)
2021年
Near infrared light triggered ternary synergistic cancer therapy via L-arginine-loaded nanovesicles with modification of PEGylated indocyanine green, Kesi Wang, Linping Jiang, Liyan Qiu*, Acta Biomaterialia, 2021. (pdf)
Vesicular IFN-γ as a cooperative attacker to enhance anti-cancer effect of 5-fluorouracil via thymidine phosphorylase upregulation and tumor microenvironment normalization, Yan Peng, Yumiao Hu, Liyan Qiu*, Nanomedicine: Nanotechnology, Biology and Medicine, 2021. (pdf)
6-Aminocaproic acid as a linker to improve near-infrared fluorescence imaging and photothermal cancer therapy of PEGylated indocyanine green, Qiang Hu, Kesi Wang, Liyan Qiu*, Colloids and Surfaces B: Biointerfaces, 2021. (pdf)
Vitamin E succinate with multiple functions: A versatile agent in nanomedicine-based cancer therapy and its delivery strategies, Lina Liang, Liyan Qiu*,International Journal of Pharmaceutics, 2021. (pdf)
Drug -driven self-assembly of pH-sensitive nano-vesicles with high loading capacity and anti-tumor efficacy, Yaomin Zhai, Juan Wang, Liyan Qiu*, Biomaterials Science, 2021. (pdf)
Mitochondria-targeted vitamin E succinate delivery for reversal of multidrug resistance, Lina Liang, Yan Peng, Liyan Qiu*, Journal of Controlled Release, 2021. (pdf)
2020年
Polymeric nano-vesicles via intermolecular action to load and orally deliver insulin with enhanced hypoglycemic effect, Yumiao Hu, Juan Wang, Liyan Qiu*, RSC Advances, 2020. (pdf)
Nano-vesicles based on phospholipid-like amphiphilic polyphosphazenes to orally deliver ovalbumin antigen for evoking anti-tumor immune response, Yurun Shen, Yumiao Hu, Liyan Qiu*, Acta Biomaterialia, 2020. (pdf)
Effective oral delivery of gp100 plasmid vaccine against metastatic melanoma through multi-faceted blending-by-blending nanogels，Jun Fu, Liyan Qiu*,Nanomedicine: Nanotechnology, Biology and Medicine, 2019. (pdf)
2018年
Photo-crosslinked and esterase-sensitive polymersome for improved antitumor effect of water-soluble chemotherapeutics，Yurun Shen, Liyan Qiu*,Nanomedicine, 2018. (pdf)
Effective intracellular delivery and Th1 immune response induced by ovalbumin loaded in pH-responsive polyphosphazene polymersomes,Menghua Gao, Yan Peng, Liming Jiang, Liyan Qiu*, Nanomedicine: Nanotechnology, Biology and Medicine, 2018. (pdf)
Dual-responsive recurrent self-assembly of a supramolecular polymer based on the host-guest complexation interaction between β-cyclodextrin and azobenzene , Ping Shen, Liyan Qiu*, New Journal of Chemistry, 2018. (pdf)
Design of pH-Sensitive Nanovesicles via cholesterol analogue incorporation for improving in vivo delivery of chemotherapeutics, Lina Liang, Jun Fu, Liyan Qiu*, ACS Applied Materials & Interfaces, 2018. (pdf)
2017年
Optimizing Hydrophobic Groups in Amphiphiles to Induce GoldNanoparticle Complex Vesicles for Stability Regulation, Jun Fu, Liyan Qiu*, Langmuir, 2017.(pdf)
Loading docetaxel in β-cyclodextrin-based micelles for enhanced oral chemotherapy through inhibition of P-glycoprotein mediated efflux transport, Lu Zhang, Yurun Shen, Liyan Qiu*, RSC Advances,2017.(pdf)
Water-Soluble Combretastatin A4 Phosphate Orally Delivered via Composite Nanoparticles With Improved Inhibition Effect Toward S180 Tumors, Yurun Shen, Liping Wu, Liyan Qiu*, Journal of pharmaceutical sciences, 2017.(pdf)
In Situ Generated Gold Nanoparticle Hybrid Polymersomes for Water-Soluble Chemotherapeutics: Inhibited Leakage and pH-Responsive Intracellular Release, Jun Fu, Lina Liang, Liyan Qiu*, Advanced Functional Materials, 2017.(pdf)
2016年
Electroneutralcompositepolymersomes self-assembled by amphiphilic polyphosphazenes for effective miR-200c in vivo delivery to inhibit drug resistant lung cance, Yan Peng, Xiumei Zhu, Liyan Qiu*, Biomaterials, 2016, 106: 1-12.(pdf)
Polyphosphazene vesicles for co-delivery of doxorubicin and chloroquine with enhanced anticancer efficacy by drug resistance reversal, Jing Xu, Xiumei Zhu,Liyan Qiu*, International journal of pharmaceutics, 2016, 498(1): 70-81.(pdf)
Constructing aptamer anchored nanovesicles for enhanced tumor penetration and cellular uptake of water soluble chemotherapeutics, Xin Li, Xiumei Zhu, Li Yan Qiu*, Acta Biomaterialia, 2016,35: 269-279 (pdf)
Reverse micelles-in-microspheres with sustained release of water-soluble combretastatin A4 phosphate for S180 tumor treatment, Liping Wu, Liyan Qiu*, Journal of Materials Chemistry B, 2016, 4(4): 760-767.(pdf)
Polymersomes via Self-Assembly of Amphiphilic β-Cyclodextrin-Centered Triarm Star Polymers for Enhanced Oral Bioavailability of Water-Soluble Chemotherapeutics, Mengying Hu, Yurun Shen, Lu Zhang,Liyan Qiu*, Biomacromolecules, 2016, 17(3): 1026-1039.(pdf)
Mechanism study of PEGylated polyester and β-cyclodextrin integrated micelles on drug resistance reversal in MRP1-overexpressed HL60/ARD cells, Qian Ji, Liyan Qiu*, Colloids and Surfaces B: Biointerfaces, 2016, 144: 203-213 (pdf)
Weakly cationic polyphosphazene vesicles for cancer immunotherapy by efficient in vivo cytokine IL-12 plasmid DNA delivery, Menghua Gao, Xiumei Zhu, Liping Wu, Liyan Qiu, Biomacromolecules, 2016, 17(6), 2199-2209(pdf)
Optimizing particle size of docetaxel-loaded micelles for enhanced treatment of oral epidermoid carcinoma, Yang Yu, Liyan Qiu*, Nanomedicine: Nanotechnology, Biology, and Medicine, 2016,12: 1941-1949 (pdf)
Multidrug-resistant malignant cells by liposomes co-encapsulating doxorubicin and chloroquine through autophagic inhibition, Menghua Gao, Yuzhen Xu, Liyan Qiu*, Journal of Liposome Research(pdf)
Synergistic effects of A-B-C type amphiphilic copolymer on reversal of drug resistance in MCF-7/ADR breast carcinoma, Lu Zhang, Jiafei Lu, Liyan Qiu*, International Journal of Nanomedicine (pdf)
Reversal of P-glycoprotein-mediated multidrug resistance by doxorubicin and quinine co-loaded liposomes in tumor cells, Qiying Shen, Liyan Qiu*, Journal of Liposome Research, 2016: 1-9.
Sequentially dual-targeting vectors with nano-in-micro structure for improved docetaxel oral delivery in vivo, Yurun Shen, Mengying Hu, Liyan Qiu*, Nanomedicine (pdf)
2015年
Co-Encapsulation of Combretastatin-A4 Phosphate and Doxorubicin in Polymersomes for Synergistic Therapy Nasopharyngeal Epidermal Carcinoma, Jinfang Zhu, Xiaoping Xu, Mengying Hu, Liyan Qiu*, Journal of biomedical nanotechnology, 2015, 11(6): 997-1006.(pdf)
Enhanced combination therapy effect on paclitaxel-resistant carcinoma by chloroquine co-delivery via liposomes, Menghua Gao, Yuzhen Xu, Liyan Qiu*, International journal of nanomedicine, 2015, 10: 6615.(pdf)
Nonspecifically enhanced therapeutic effects of vincristine on multidrug-resistant cancers when coencapsulated with quinine in liposomes, Yuzhen Xu, Liyan Qiu*, International journal of nanomedicine, 2015, 10: 4225. (pdf)
Thermo-responsive triblock copolymer micelles containing PEG 6000 for either water-soluble or water-insoluble drug sustained release and treatment, Jun Fu, Xinyi Lv, Liyan Qiu*, RSC Advances, 2015, 5(47): 37451-37461.(pdf)
Indocyanine green targeted micelles with improved stability for near-infrared image-guided photothermal tumor therapy, Lu Yan, Liyan Qiu*, Nanomedicine, 2015, 10(3): 361-373.(pdf)
Targeted delivery of anticancer drugs by aptamer AS1411 mediated Pluronic F127/cyclodextrin-linked polymer composite micelles, Xin Li, Yang Yu, Qian Ji ,Liyan Qiu*,Nanomedicine: Nanotechnology, Biology and Medicine ,2015, 11(1): 175-184.(pdf)
2014年
The anti-tumor efficacy of curcumin when delivered by size/charge-changing multistage polymeric micelles based on amphiphilic poly(β-amino ester) derivates, Yang Yu, Xiaoli Zhang, Liyan Qiu*, Biomaterials 2014, 35:3467-3479 (pdf)
High loading of hydrophilic/hydrophobic doxorubicin into polyphosphazene polymersome for breast cancer therapy, Jing Xu, Qinghe Zhao, Yangmin Jin, Liyan Qiu*, Nanomedicine: Nanotechnology, Biology and Medicine, 2014,10(2): 349-358 (pdf)
2013年
Smart ligand: Aptamer-mediated targeted delivery of chemotherapeutic drugs and siRNA for cancer therapy, Xin Li, Qinghe Zhao, Liyan Qiu*, Journal of Controlled Release, 2013, 171(2): 152-162 (pdf)
Thermosensitive β-cyclodextrin modified poly(e-caprolactone)-poly(ethylene glycol)- poly(e-caprolactone) micelles prolong the anti-inflammatory effect of indomethacin following local injection，Xiawei Wei, Xinyi Lv, Qinghe Zhao, Liyan Qiu*，Acta Biomaterialia 2013, 9: 6953-6963 (pdf)
2013年以前
Mechanisms of drug resistance reversal in dox-resistant MCF-7 Cells by pH-responsive amphiphilic polyphosphazene containing diisopropylamino side groups, Li Yan Qiu*, Cheng Zheng and Qinghe Zhao, Molecular Pharmaceutics, 2012, 9(5): 1109-1117 (pdf)
β-cyclodextrin-centered star-shaped amphiphilic polymers for doxorubicin delivery，Li Yan Qiu*, Rong Juan Wang, Cheng Zheng, Yi Jin, Le Qun Jin，Nanomedicine, 2010, 5 (2): 193-208 (pdf)
Versatile preparation of fluorescent particles based on polyphosphazenes: from micro- to nanoscale, JiangxiangZhang*, Liyan Qiu*, Xiaodong Li, Yi Jin and Kangjie Zhu, Small, 2007, 3(12), 2081-2093 (pdf)
Self-assembled polyethylenimine-graft-poly(ε-caprolactone) micelles as potential dual carriers of genes and anticancer drugs, Li Yan Qiu, You Han Bae, Biomaterials,2007 (28): 4132-4142 (pdf)
Indomethacin-loaded polymeric nanocarriers based on amphiphilic polyphosphazenes with poly (N-isopropylacrylamide) and ethyl tryptophan as side groups: Preparation, in vitro and in vivo evaluation, Jian Xiang Zhang, Xiao Jing Li, Li Yan Qiu*, Xiao Hui Li, Mei Qiu Yan, Yi Jin and Kang Jie Zhu，Journal of Controlled Release, 2006, 116 (3): 322-329 (pdf)
Multi-morphological self-assemblies of amphiphilic graft polyphosphazenes with oligo-poly (N-isopropylacrylamide) and ethyl 4-aminobenzoate as side groups，Jian Xiang Zhang, Li Yan Qiu, Yi Jin, Kang Jie Zhu, Macromolecules 2006，39，451-455 (pdf)
Thermosensitive micelles self-assembled by novel N-isopropylacrylamide oligomer Grafted Polyphosphazene, Jian Xiang Zhang, Li Yan Qiu*, Kang Jie Zhu, Yi Jin, Macromolecular Rapid Communications 2004, 25: 1563–1567 (pdf)
著作
Biopolymers，Volume 9: Miscellaneous Biopolymers and Biodegradation of Synthetic Polymers，Chapter 22：Biodegradation of polyphosphazenes 491-522, KJ Zhu，LY Qiu，Wiley-VCH出版社, 2003年
Biomedical Applications of Polyphosphazenes, 15 Amphiphilic Polyphosphazenes as Drug Carriers, Liyan Qiu, Cheng Zheng, 277-296, Wiley出版社，2009年6月
