Enzymatic transglycosylation of PEG brushes by β-galactosidase

Yan Fang,  Wei Xu,  Jian Wu, Zhi-Kang Xu. Chem. Commun., 2012, 48, 11208-11210

Enzymatic transglycosylation has been successfully implemented by β-galactosidase (β-Gal) on PEG brushes. Kinetic parameters validate this kind of chemoenzymatic strategy which is promising for construction of biomimetic surfaces with glycocalyx-like structures.