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Changyou Gao, Ph.D. Professor
Time:2012-05-02 13:57 Source:未知 Author:admin Click:


Department of Polymer Science and Engineering, Zhejiang University, 38 Zheda Road, Hangzhou, China 310027

Phone/Fax: +86 571 8795 1108


Other Appointments:

Deputy Director, Institute of Biomedical Macromolecules

Deputy Director, Key Laboratory of Macromolecular Synthesis and Functionalization, Ministry of Education


General Description:

His research interests are biomedical materials for tissue engineering and regenerative medicine, and colloidal and nano-biomaterials for drug delivery and cellular interaction. He was a principal investigator for National Science Fund for Distinguished Young Scholars of China (2004) and Key project of Natural Science Foundation of China (2004, 2009), and a co-investigator of the National Major State Basic Research Program of China (973 program), the National High-tech Research and Development Program (863 program) and Frame Work Program 7 of European Commission. He has published more than 200 papers in Agnew. Chem., Adv. Materials and Biomaterials etc. and has a personal H-index of 37 at present. He has delivered more than 20 keynote or plenary lectures in scientific conferences.


Professional Activities:

An Editorial Member of:

Journal of Zhejiang University: Science

Journal of Tissue Engineering and Reconstructive Surgery

Chinese Science Bulletin, Science in China: Chemistry

Progress in Chemistry

Journal of Nanoscience Letters

Colloids and Surfaces B: Biointerfaces


A Committee Member of:

Chinese Society of Biomedical Engineering, Biomaterials Division

Chinese Society of Biomedical Engineering, Tissue Engineering Division

Chinese Materials Research Society, Biomaterials Division

Chinese Society for Composite Materials, Composite Biomaterials Division



Ph.D. – Jilin University, Polymer Chemistry and Physics, 1996

M. S – Jilin University, Polymer Chemistry and Physics, 1993

B.S. – Jilin University, Polymer Materials and Engineering, 1990


Working Experience:

2001-, Prof. Department of Polymer Science and Engineering, Zhejiang University

1999-2004 (18months in total), Visiting Scholar, Max Planck Institute of Colloids and Interfaces, Germany

1999- DAAD fellowship, Max Planck Institute of Colloids and Interfaces, Germany

1998-2001, Associate Prof., Department of Polymer Science and Engineering, Zhejiang University

1996-1998, Postdoc, Department of Polymer Science and Engineering, Zhejiang University


Awards and Honors:

  1. The National Science Fund for Distinguished Young Scholars of China, 2004
  2. A Cheung Kong Scholar of Ministry of Education of China, 2008
  3. The first level award of Science and Technology of Zhejiang Province, 2008


Current Projects:

  1. Key Project of National Natural Science Foundation of China. Study on gradient biomedical polymers for mediating cell migration and differentiation, 2010.1-2013.12
  2. Partner of Frame Work Program 7 (FP 7). Health Impact of Engineered Metal and Metal Oxide Nanoparticles: Response, Bioimaging and Distribution at Cellular and Body Level,2009.10-2012.9
  3. Partner of 973 Project. Characteristics of the surfaces and interfaces of tissue inductive biomaterials and their interactions with biological system in a cellular and protein level, 2011.1-2015.12
  4. The Ministry of Science and Technology of China for the Indo-China Cooperation. Structure design and functionalization of self-assembled microcapsules for drug delivery, 2010.1-2013.6


Selected Publications:

  1. Yuying Zhang, Bing Wang, Xinan Meng, Guanqing Sun, Changyou Gao*. Influences of Acid-Treated Multiwalled Carbon Nanotubes on Fibroblasts: Proliferation, Adhesion, Migration, and Wound Healing, Annals of Biomedical Engineering, 2011, 39(1): 414-426
  2. Rui Guo, Shaojun Xu, Lie Ma,*, Aibin Huang, Changyou Gao*. The healing of full-thickness burns treated by using plasmid DNA encoding VEGF-165 activated collagenechitosan dermal equivalents, Biomaterials, 2011, 32: 1019-1031.
  3. Wei Wang, Bo Li, Junzhou Yang, Long Xin, Yanglin Li, Hongpin Yin, Yiying Qi, Yangzi Jiang, Hongwei Ouyang, Changyou Gao*. The restoration of full-thickness cartilage defects with BMSCs and TGF-beta 1 loaded PLGA/fibrin gel constructs, Biomaterials, 2010, 31: 8964-8973.
  4. Yuying Zhang, Ling Hu, Dahai Yu, Changyou Gao*. Influence of silica particle internalization on adhesion and migration of human dermal fibroblasts, Biomaterials 2010, 31: 8465-8474.
  5. Rui Guo, Shaojun Xu, Lie Ma*, Aibin Huang, Changyou Gao*. Enhanced angiogenesis of gene-activated dermal equivalent for treatment of full thickness incisional wounds in a porcine model, Biomaterials, 2010, 31: 7308-7320.
  6. Wei Wang, Bo Li, Yanglin Li, Yangzi Jiang, Hongwei Ouyang, Changyou Gao*. In vivo restoration of full-thickness cartilage defects by poly(lactide-co-glycolide) sponges filled with fibrin gel, bone marrow mesenchymal stem cells and DNA complexes, Biomaterials 2010, 31: 5953-5965
  7. Zhengwei Mao, Haifei Shi, Rui Guo, Lie Ma,* Changyou Gao*, Chunmao Han, Jiacong Shen. Enhanced angiogenesis of porous collagen scaffolds by incorporation of TMC/DNA complexes encoding vascular endothelial growth factor, Acta Biomaterialia, 2009, 5: 2983–2994.
  8. Huaping Tan, Jindan Wu, Lihong Lao, Changyou Gao*. Gelatin/chitosan/hyaluronan scaffold integrated with PLGA microspheres for cartilage tissue engineering, Acta Biomaterialia, 2009, 5: 328-337
  9. Xiao Gong, Jie Yang, Lulu Han, Changyou Gao*. Influence of Drying Time of Polyelectrolyte Multilayers on the Compression-Induced Pattern Formation, Langmuir, 2008, 24(24): 13925-13933
  10. Linhui Li, Yang Zhu, Bo Li, Changyou Gao*. Fabrication of Thermoresponsive Polymer Gradients for Study of Cell Adhesion and Detachment, Langmuir, 2008, 24, 13632-13639
  11. Yi Zhu, Weijun Tong, Changyou Gao*, Helmuth Möhwald. Assembly of polymeric micelles into hollow microcapsules with extraordinary stability against extreme pH conditions, Langmuir, 2008, 24: 7810-7816
  12. Weijun Tong, Changyou Gao*. Multilayer microcapsules with tailored structures for bio-related applications [review], Journal of Materials Chemistry, 2008, 18: 3799–3812
  13. Zhipeng Wang, Zhiqiang Feng, Changyou Gao*. Stepwise assembly of the same polyelectrolytes using host-guest interaction to obtain microcapsules with multiresponsive properties, Chemistry of Materials, 2008, 20(13): 4194-4199
  14. Zhiqiang Feng, Zhipeng Wang, Changyou Gao*, Jiacong Shen. Direct Covalent Assembly to Fabricate Microcapsules with Ultrathin Walls and High Mechanical Strength, Advanced Materials, 2007, 19 (21): 3687-3691
  15. Zhiqiang Feng, Zhipeng Wang, Changyou Gao*, Jiacong Shen. Template Polymerization to Fabricate Hydrogen-Bonded Poly(acrylic acid)/Poly(vinylpyrrolidone) Hollow Microcapsules with a pH-Mediated Swelling-Deswelling Property, Chem. Mater. 2007, 19, 4648-4657
  16. Zhengwei Mao, Bo Wang, Lie Ma, Changyou Gao* and Jiacong Shen. The influence of polycaprolactone coating on the internalization and cytotoxicity of gold nanoparticles, Nanomedicine: Nanotechnology, Biology, and Medicine, 2007, 3: 215-223
  17. Yihong Gong, Yabin Zhu, Yunxiao Liu, Zuwei Ma, Changyou Gao*, Jiacong Shen.Layer-by-layer assembly of chondroitin sulfate and collagen on aminolyzed poly(l-lactic acid) porous scaffolds to enhance their chondrogenesis, Acta Biomaterialia, 2007, 3: 677-685
  18. Zhengwei Mao, Lie Ma*, Jiang Yan, Ming Yan, Changyou Gao*, Jiacong Shen. The gene transfection efficiency of thermoresponsive N,N,N-trimethyl chitosan chloride-g-poly(N-isopropylacrylamide) copolymer, Biomaterials,2007, 28: 4488-4500